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Domestic Scheduled Flights
| Origin | Destination | Carier |
| TUS | DCA Washington, DC, DC US | America West Airlines |
| TUS | EWR Newark, NJ US | America West Airlines |
| TUS | JFK New York City, NY US | America West Airlines |
| TUS | DCA Washington, DC, DC US | American Airlines |
| TUS | IAD Washington, DC, DC US | American Airlines |
| TUS | DFW Dallas / Ft Worth, TX US | American Airlines |
| TUS | HOU Houston, TX US | American Airlines |
| TUS | IAH Houston, TX US | American Airlines |
| TUS | JFK New York City, NY US | American Airlines |
| TUS | LGA New York City, NY US | American Airlines |
| TUS | MDW Chicago, IL US | American Airlines |
| TUS | ORD Chicago, IL US | American Airlines |
| TUS | TPA Tampa, FL US | American Airlines |
| TUS | DAL Dallas, TX US | Continental Airlines |
| TUS | EWR Newark, NJ US | Continental Airlines |
| TUS | IAH Houston, TX US | Continental Airlines |
| TUS | LGA New York City, NY US | Continental Airlines |
| TUS | TPA Tampa, FL US | Delta Air Lines |
| TUS | MDW Chicago, IL US | Frontier Airlines |
| TUS | JFK New York City, NY US | JetBlue Airways |
| TUS | ASE Aspen, CO | Mesa Airlines, Inc. |
| TUS | BFL Bakersfield, CA | Mesa Airlines, Inc. |
| TUS | BOI Boise, ID | Mesa Airlines, Inc. |
| TUS | BUR Burbank, CA | Mesa Airlines, Inc. |
| TUS | CLD Carlsbad, CA | Mesa Airlines, Inc. |
| TUS | CMH Columbus, OH | Mesa Airlines, Inc. |
| TUS | COS Colorado Springs, CO | Mesa Airlines, Inc. |
| TUS | DFW Dallas/Fort Worth, TX | Mesa Airlines, Inc. |
| TUS | DRO Durango, CO | Mesa Airlines, Inc. |
| TUS | DSM Des Moines, IA | Mesa Airlines, Inc. |
| TUS | ELP El Paso, TX | Mesa Airlines, Inc. |
| TUS | EUG Eugene, OR | Mesa Airlines, Inc. |
| TUS | FAT Fresno, CA | Mesa Airlines, Inc. |
| TUS | FLG Flagstaff, AZ | Mesa Airlines, Inc. |
| TUS | GJT Grand Junction, CO | Mesa Airlines, Inc. |
| TUS | ICT Wichita, KS | Mesa Airlines, Inc. |
| TUS | LAS Las Vegas, NV | Mesa Airlines, Inc. |
| TUS | LAX Los Angeles, CA | Mesa Airlines, Inc. |
| TUS | LGB Long Beach, CA | Mesa Airlines, Inc. |
| TUS | MRY Monterey, CA | Mesa Airlines, Inc. |
| TUS | MTJ Montrose, CO | Mesa Airlines, Inc. |
| TUS | PHX Phoenix, AZ | Mesa Airlines, Inc. |
| TUS | PSP Palm Springs, CA | Mesa Airlines, Inc. |
| TUS | RNO Reno, NV | Mesa Airlines, Inc. |
| TUS | SAN San Diego, CA | Mesa Airlines, Inc. |
| TUS | SAT San Antonio, TX | Mesa Airlines, Inc. |
| TUS | SBA Santa Barbara, CA | Mesa Airlines, Inc. |
| TUS | SBP San Luis Obispo, CA | Mesa Airlines, Inc. |
| TUS | SCK Stockton, CA | Mesa Airlines, Inc. |
| TUS | SFO San Francisco, CA | Mesa Airlines, Inc. |
| TUS | SLC Salt Lake City, UT | Mesa Airlines, Inc. |
| TUS | TEX Telluride, CO | Mesa Airlines, Inc. |
| TUS | YUM Yuma, AZ | Mesa Airlines, Inc. |
| TUS | BFL Bakersfield, CA | Sky West Airlines, Inc. |
| TUS | CEC Crescent City, CA | Sky West Airlines, Inc. |
| TUS | CLD Carlsbad, CA | Sky West Airlines, Inc. |
| TUS | COS Colorado Springs, CO | Sky West Airlines, Inc. |
| TUS | DEN Denver, CO | Sky West Airlines, Inc. |
| TUS | DFW Dallas/Fort Worth, TX | Sky West Airlines, Inc. |
| TUS | FAT Fresno, CA | Sky West Airlines, Inc. |
| TUS | IPL El Centro, CA | Sky West Airlines, Inc. |
| TUS | IYK Inyokern, CA | Sky West Airlines, Inc. |
| TUS | LAS Las Vegas, NV | Sky West Airlines, Inc. |
| TUS | LAX Los Angeles, CA | Sky West Airlines, Inc. |
| TUS | MRY Monterey, CA | Sky West Airlines, Inc. |
| TUS | OAK Oakland, CA | Sky West Airlines, Inc. |
| TUS | ONT Ontario, CA | Sky West Airlines, Inc. |
| TUS | OXR Oxnard, CA | Sky West Airlines, Inc. |
| TUS | PHX Phoenix, AZ | Sky West Airlines, Inc. |
| TUS | PSP Palm Springs, CA | Sky West Airlines, Inc. |
| TUS | SAN San Diego, CA | Sky West Airlines, Inc. |
| TUS | SBA Santa Barbara, CA | Sky West Airlines, Inc. |
| TUS | SBP San Luis Obispo, CA | Sky West Airlines, Inc. |
| TUS | SFO San Francisco, CA | Sky West Airlines, Inc. |
| TUS | SGU St. George, UT | Sky West Airlines, Inc. |
| TUS | SJC San Jose, CA | Sky West Airlines, Inc. |
| TUS | SLC Salt Lake City, UT | Sky West Airlines, Inc. |
| TUS | SMF Sacramento, CA | Sky West Airlines, Inc. |
| TUS | SMX Santa Maria, CA | Sky West Airlines, Inc. |
| TUS | SNA Santa Ana, CA | Sky West Airlines, Inc. |
| TUS | VIS Visalia, CA | Sky West Airlines, Inc. |
| TUS | YUM Yuma, AZ | Sky West Airlines, Inc. |
| TUS | DAL Dallas, TX US | Southwest Airlines |
| TUS | HOU Houston, TX US | Southwest Airlines |
| TUS | MDW Chicago, IL US | Southwest Airlines |
| TUS | IAD Washington, DC, DC US | United Airlines |
There is over 86 domestic flights from TUS airport.
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