Domestic and international flight routes departing from Luiz Munoz International Airport.
Domestic Scheduled Flights
| Origin | Destination | Carier |
| SJU | STT Charlotte Amalie, VI | Air St. Thomas |
| SJU | STT Charlotte Amalie, VI | Air Sunshine, Inc. |
| SJU | STX St. Croix, VI | Air Sunshine, Inc. |
| SJU | PSE Ponce, PR | Cape Air |
| SJU | STT Charlotte Amalie, VI | Cape Air |
| SJU | STX St. Croix, VI | Cape Air |
| SJU | IAD Washington, DC, DC US | United Airlines |
| SJU | ORD Chicago, IL US | United Airlines |
| SJU | STT Charlotte Amalie St Thomas, VI US | United Airlines |
| SJU | BOS Boston, MA US | US Airways |
| SJU | CLT Charlotte, NC US | US Airways |
| SJU | IAD Washington, DC, DC US | US Airways |
| SJU | PHL Philadelphia, PA US | US Airways |
| SJU | PIT Pittsburgh, PA US | US Airways |
| SJU | VQS Vieques, PR | Vieques Air Link, Inc. |
There are 15+ domestic flights from SJU airport.
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